Disease: Cholestasis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TMED7 Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 0.48 0.436 0.808
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
RDX P35241 radixin Cellular structure 0.85 0.593 0.615
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
ONECUT1 Q9UBC0 one cut homeobox 1 Transcription factor 0.52 0.686 0.346
NR0B2 Q15466 nuclear receptor subfamily 0 group B member 2 Nuclear receptor 8.3E-06 0.474 0.808
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
LOXL2 Q9Y4K0 lysyl oxidase like 2 3.4E-07 0.527 0.731
LOC102724197 inactive glutathione hydrolase 2 0.559 0.731
KRT7 P08729 keratin 7 3.1E-12 0.463 0.808
KRT19 P08727 keratin 19 4.3E-03 0.460 0.731
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885